File:Subhash nucleoid 01.png

Original file (4,148 × 1,671 pixels, file size: 560 KB, MIME type: image/png)

Summary

Description
English: Formation of the Escherichia coli nucleoid A. An illustration of an open conformation of the circular genome of Escherichia coli. Arrows represent bi-directional DNA replication. The genetic position of the origin of bi-directional DNA replication (oriC) and the site of chromosome decatenation (dif) in the replication termination region (ter) are marked. Colors represent specific segments of DNA as discussed in C. B. An illustration of a random coil form adopted by the pure circular DNA of Escherichia coli at thermal equilibrium without supercoils and additional stabilizing factors.[5][6] C. A cartoon of the chromosome of a newly born Escherichia coli cell. The genomic DNA is not only condensed by 1000-fold compared to its pure random coil form but is also spatially organized. oriC and dif are localized in the mid-cell, and specific regions of the DNA indicated by colors in A organize into spatially distinct domains. Six spatial domains have been identified in E. coli. Four domains (Ori, Ter, Left, and Right) are structured and two (NS-right and NS-left) are non-structured (See section 4 of the main text for details). The condensed and organized form of the DNA together with its associated proteins and RNAs is called nucleoid.
Date
Source doi:10.1371/journal.pgen.1008456 Verma SC, Qian Z, Adhya SL (2019) Architecture of the Escherichia coli nucleoid. PLoS Genet 15(12): e1008456.
Author Subhash C. Verma, Zhong Qian, Sankar L. Adhya

Licensing

w:en:Creative Commons
attribution
This file is licensed under the Creative Commons Attribution 4.0 International license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

Captions

Add a one-line explanation of what this file represents

Items portrayed in this file

depicts

12 December 2019

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current00:15, 18 December 2019Thumbnail for version as of 00:15, 18 December 20194,148 × 1,671 (560 KB)Evolution and evolvabilityUser created page with UploadWizard

The following page uses this file:

Global file usage

The following other wikis use this file:

Metadata