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Summary
| Description |
English: High magnification micrograph of melanosis coli (MC), also pseudomelanosis coli (PMC). Colonic biopsy. HPS stain.
Melanosis coli is a misnomer, as the pigmentation is due to lipofuscin-laden macrophages - not melanin pigment. Pseudomelanosis coli is a more appropriate descriptor, but not in common usage. The differential diagnosis of brown pigmentation of the colon is:
PMC is predominantly seen in the cecum and right colon (ascending colon) and associated with anthracene laxative use such as senna (Senokot). Related images
Another case:
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| Source | Own work |
| Author | Nephron |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 02:08, 22 October 2009 | | 2,848 × 4,272 (3.82 MB) | Nephron | {{Information |Description={{en|1=High magnification micrograph of '''melanosis coli''' (MC), also '''pseudomelanosis coli''' (PMC). Colonic biopsy. H&E stain. Melan |
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