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File:Extramammary Pagets disease low.jpg

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Summary

Description

Low magnification micrograph of extramammary Paget's disease. H&E stain.

The image only shows the epidermal layer, which contains large cells with clear cytoplasm. The H&E slide is not definitive; the clear cells may represent:

The definitive diagnosis is determined with immunohistochemical stains (S-100 -ve and HMB-45 -ve (both typically +ve in melanoma), CK7 +ve, CEA +ve (-ve in Bowen's disease, -ve in Toker cells).

The histologic appearance of Paget's disease of the breast is identical to extramammary Paget's disease, i.e. it is not possible to say this is extramammary from the image alone.

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Author Nephron
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Date/TimeThumbnailDimensionsUserComment
current02:10, 15 July 2009Thumbnail for version as of 02:10, 15 July 20094,272 × 2,848 (2.09 MB)Nephron{{Information |Description=Low magnification micrograph of extramammary Paget's disease. H&E stain. The image only shows the epidermal layer, which contains large cells with clear cytoplas
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