English: The structure of the HIV reverse transcriptase (RT) heterodimer in complex with an RNA:DNA duplex. The reverse transcriptase p66 fragment is shown in yellow with the C-terminal RNase H domain shown in blue (active site residues in magenta spheres). The orange strand is RNA and the red strand is DNA. The p51 fragment - a differently processed protein equivalent to p66 without the RNase H domain - is shown in green.
Rendered from PDB 1HYS.
Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA.
Sarafianos, S.G., Das, K., Tantillo, C., Clark Jr., A.D., Ding, J., Whitcomb, J.M., Boyer, P.L., Hughes, S.H., Arnold, E.
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{{Information |Description ={{en|1=The structure of the HIV reverse transcriptase (RT) heterodimer in complex with an RNA:DNA duplex. The reverse transcriptase p66 fragment is shown in yellow with the C-terminal RNase H domain shown in blue (active...
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