Iron(II) fumarate

(Redirected from Ferrous fumarate)

Iron(II) fumarate, also known as ferrous fumarate, is the iron(II) salt of fumaric acid, occurring as a reddish-orange powder, used to supplement iron intake. It has the chemical formula C4H2FeO4. Pure ferrous fumarate has an iron content of 32.87%, therefore one tablet of 300 mg iron fumarate will contain 98.6 mg of iron (548% Daily Value based on 18 mg RDI).

Iron(II) fumarate
Names
IUPAC name
Iron(2+) (2E)-but-2-enedioate
Other names
Ferrous fumarate; Feostat
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.004.953 Edit this at Wikidata
UNII
  • InChI=1S/C4H4O4.Fe/c5-3(6)1-2-4(7)8;/h1-2H,(H,5,6)(H,7,8);/q;+2/p-2/b2-1+; checkY
    Key: PMVSDNDAUGGCCE-TYYBGVCCSA-L checkY
  • InChI=1/C4H4O4.Fe/c5-3(6)1-2-4(7)8;/h1-2H,(H,5,6)(H,7,8);/q;+2/p-2/b2-1+;
    Key: PMVSDNDAUGGCCE-FMKVMNOJBF
  • [Fe+2].[O-]C(=O)/C=C/C([O-])=O
Properties
C4H2FeO4
Molar mass 169.901 g·mol−1
Appearance reddish-brown powder
Odor odorless
Density 2.435 g/cm3 (20 °C)
Melting point 280 °C (536 °F; 553 K)
slightly soluble
Pharmacology
B03AA02 (WHO)
Hazards
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 1: Exposure would cause irritation but only minor residual injury. E.g. turpentineFlammability 0: Will not burn. E.g. waterInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
1
0
0
Lethal dose or concentration (LD, LC):
3850 mg/kg (oral, rat)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Iron supplement

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Ferrous fumarate is often taken orally as an iron supplement to treat or prevent iron deficiency anemia.[1] Mixtures of ferrous fumarate and potassium iodate, "double fortified salt", are used to address both iron and iodine deficiencies.[2]

See also

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References

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  1. ^ Santiago, Palacios (2012-05-02). "Ferrous versus Ferric Oral Iron Formulations for the Treatment of Iron Deficiency: A Clinical Overview". The Scientific World Journal. 2012: e846824. doi:10.1100/2012/846824. ISSN 2356-6140. PMC 3354642. PMID 22654638.
  2. ^ Diosady, Levente L.; Mannar, M.G. Venkatesh; Krishnaswamy, Kiruba (2019). "Improving the lives of millions through new double fortification of salt technology". Maternal & Child Nutrition. 15 (Suppl 3): e12773. doi:10.1111/mcn.12773. PMC 6594086. PMID 31148400.