Cranioschisis (Greek: κρανιον kranion, "skull", and σχίσις schisis, "split"), is a skull-related neural tube defect. The skull does not close all the way in this deformity (especially at the occipital region). As a result, the amniotic fluid enters the brain, leading to eventual brain degeneration and anencephaly.[1] Craniorachischisis is on the extreme end of the dysraphism spectrum, wherein the entire length of the neural tube fails to close.[2]
| Cranioschisis | |
|---|---|
| Specialty | Neurology |
See also
editReferences
edit- ^ Singh, D.R. (2017). Essentials of Anatomy for Dentistry Students. Wolters Kluwer India Pvt. Limited. p. 359. ISBN 978-93-5129-620-1. Retrieved January 2, 2024.
- ^ Larsen's Human Embryology (5 ed.). Churchill Livingstone. 2015. pp. 81–107.
Further reading
edit- Marin-Padilla, Miguel (1965). "Study of the Skull in Human Cranioschisis". Cells Tissues Organs. 62 (1). S. Karger AG: 1–20. doi:10.1159/000142740. ISSN 1422-6405. PMID 5864445.
- Padmanabhan, R. (1988). "Light microscopic studies on the pathogenesis of exencephaly and cranioschisis induced in the rat after neural tube closure". Teratology. 37 (1): 29–36. doi:10.1002/tera.1420370106. ISSN 0040-3709. PMID 3347905.
External links
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