Different for Girls may refer to:
- Different for Girls (film), a 1996 film starring Rupert Graves and Steven Mackintosh
- Different for Girls (Leslie Mills album), 2003 album by Leslie Mills
- "It's Different for Girls", 1979 song by Joe Jackson
- "Different for Girls" (Dierks Bentley song), 2016
- "It's Different for Girls", a 2016 song by of Montreal from Innocence Reaches
- "Different for Girls", a 2013 song by Gavin DeGraw from Make a Move