Dexbrompheniramine/pseudoephedrine

Dexbrompheniramine/pseudoephedrine (trade name Drixoral) is a combination medication that contains the antihistamine dexbrompheniramine maleate and the decongestant pseudoephedrine sulfate. It was used to treat symptoms associated with allergies and colds such as itchy and watery eyes, runny nose, nasal and sinus congestion, and sneezing. Because it contains pseudoephedrine, its purchase in the United States was severely restricted by the Combat Methamphetamine Epidemic Act of 2005 over fears that any product containing pseudoephedrine can be used to make methamphetamine.[1]

Dexbrompheniramine/pseudoephedrine
Combination of
DexbrompheniramineAntihistamine
PseudoephedrineDecongestant
Clinical data
Trade namesDrixoral
AHFS/Drugs.comMicromedex Detailed Consumer Information
ATC code
Legal status
Legal status
Identifiers
CAS Number

Availability

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As of 2008, Drixoral was removed from the US market by manufacturer Merck. The company's updated website attributes "changing [their] manufacturing location" for the supply disruption and currently states "it is unlikely product will be available in 2010".[2] However, the trade name Drixoral is now used in Canada for an oxymetazoline hydrochloride nasal spray.[3]

Commercials

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Drixoral was a very popular cold relief medicine advertised on U.S. television in the 1980s. Many of their commercials were narrated by the late Burgess Meredith. [4]

References

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  1. ^ Payne JW (9 March 2009). "Drixoral: Why the Allergy Medicine Isn't Available, and What to Use Instead". U.S. News & World Report. Retrieved 22 February 2010.
  2. ^ "Products Currently Unavailable". Merck. 2010. Retrieved 18 May 2010.
  3. ^ "Product Information:Drixoral". Health Canada. Retrieved 12 January 2024.
  4. ^ "1988 Drixoral Commercial". Drixoral. 1988. Retrieved 21 March 2021.