CTU2 (formerly known as C16orf84) is a human gene located on chromosome 16.[5] The mRNA encodes the longer isoform. The gene encodes a cytoplasmic protein that plays a probable role in tRNA modification.[6]
| CTU2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | CTU2, C16orf84, NCS2, UPF0432, cytosolic thiouridylase subunit 2, MFRG | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 617057; MGI: 1914215; HomoloGene: 79815; GeneCards: CTU2; OMA:CTU2 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
References
edit- ^ a b c GRCh38: Ensembl release 89: ENSG00000174177 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000049482 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: C16orf84". 24 December 2015.
- ^ "NCBI protein: cytoplasmic tRNA 2-thiolation protein 2 isoform 1".
External links
edit- Human CTU2 genome location and CTU2 gene details page in the UCSC Genome Browser.
Further reading
edit- Schlieker CD, Van der Veen AG, Damon JR, Spooner E, Ploegh HL (November 2008). "A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway". Proc. Natl. Acad. Sci. U.S.A. 105 (47): 18255–60. Bibcode:2008PNAS..10518255S. doi:10.1073/pnas.0808756105. PMC 2584574. PMID 19017811.
- Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP (August 2008). "A quantitative atlas of mitotic phosphorylation". Proc. Natl. Acad. Sci. U.S.A. 105 (31): 10762–7. Bibcode:2008PNAS..10510762D. doi:10.1073/pnas.0805139105. PMC 2504835. PMID 18669648.
 | This article on a gene on human chromosome 14 is a stub. You can help Wikipedia by expanding it. |